产品名称:α-Tubulin单克隆抗体(3G5)

产品英文名称:Anti-α-Tubulin Monoclonal Antibody (3G5)

货号:ABL1080

货期:期货(3天内发货)

特点&优势:
Null

背景:
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. TUBA1A encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that TUBA1A expression is predominantly found in morphologically differentiated neurologic cells. TUBA1A is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

免疫原:重组蛋白

宿主:小鼠

反应性:人#小鼠#大鼠

标签:Null

检测类型:WB#IHC-P#IF#IP

克隆类型:单克隆

亚型:小鼠IgG

纯化工艺:通过使用特异性免疫原的亲和层析,从小鼠腹水中纯化抗体。

偶联物:Null

产品形式:液体形式

浓度:Null

α-Tubulin单克隆抗体(3G5)注意事项:Null

储存缓冲液:PBS缓冲液(pH 7.4),含有0.5%BSA(稳定剂),0.02%叠氮化钠(防腐剂)和50%甘油。

保存建议:自发货之日起,-20°C可稳定保存1年。为最大限度的避免损失,请在打开管盖之前融化抗体并离心。我们建议使用前分装以避免反复冻融。

运输条件:冰袋运输(蓝冰)

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