产品名称:重组人白介素11(IL-11)

产品英文名称:Human IL-11 Protein

货号:PRP1952

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<1.0 EU。

重组人白介素11(IL-11)产品背景:
IL-11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation, and could be used as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

序列:
氨基酸序列来源于:人源IL 11 (Pro22-Leu199) (P20809) 表达的蛋白片段。

标签:无标签

活性:
通过其在TF-1细胞中诱导增殖的能力来测定。该效应的ED50为1.982 ng/mL。

蛋白长度:
重组人 IL11由178个氨基酸组成,预测分子量为19.14 KD。

分子:
IL11; AGIF; Adipogenesis Inhibitory Factor; Oprelvekin; IL-11; IL 11

检测指标:
IL11; AGIF; Adipogenesis Inhibitory Factor; Oprelvekin; IL-11; IL 11

产品形式:冻干粉,冻干缓冲液为无菌的20 mM Tris,150 mM NaCl,pH 7.4。

重组人白介素11(IL-11)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。