产品名称:重组小鼠脂联素蛋白,His-标签(Adiponectin)

产品英文名称:Mouse Adiponectin Protein, His tag

货号:PRP1304

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。

重组小鼠脂联素蛋白,His-标签(Adiponectin)产品背景:
Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.

序列:
氨基酸序列来源于:小鼠源Adiponectin (Q60994) (Val21-Asn247) 表达的蛋白片段。

标签:His

活性:
Testing in Progress

蛋白长度:
重组小鼠 Adiponectin 由227个氨基酸组成,预测分子量为24.6 KD。

分子:
Adiponectin

检测指标:
Adiponectin

产品形式:冻干粉,冻干缓冲液为无菌的20 mM Tris,150 mM NaCl,pH 8.0。

重组小鼠脂联素蛋白,His-标签(Adiponectin)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于110 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。