产品名称:重组人成纤维生长因子19,His-标签(FGF-19)

产品英文名称:Human FGF-19 Protein, His tag

货号:PRP1235

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。

重组人成纤维生长因子19,His-标签(FGF-19)产品背景:
Fibroblast growth factor 19 (FGF-19) is a secreted protein which belongs to the FGFs family. FGF-19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF-19 can be considered as a regulator of energy expenditure.

序列:
氨基酸序列来源于:人源 FGF19 (Arg22-Lys216) (O95750) 表达的蛋白片段。

标签:His-标签

活性:
Testing in Progress

蛋白长度:
重组人FGF19 由195个氨基酸组成,预测分子量为21.8 KD。

分子:
FGF-19

检测指标:
FGF-19

产品形式:冻干粉,冻干缓冲液为无菌的20 mM Tris, 50 mM NaCl, pH8.0.

重组人成纤维生长因子19,His-标签(FGF-19)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。