产品名称:重组人干扰素α1a(IFN-α1a)

产品英文名称:Human IFN-α1a protein

货号:PRP1218

产品特点&优势:
通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。

重组人干扰素α1a(IFN-α1a)产品背景:
Interferon-α1 is a member of the Type I IFN family best known for their antiviral activity. Most nucleated cells produce one or more Type I IFNs in response to viral infection. Secreted Type I IFN then induces viral protective responses in neighboring non-infected cells. Type I IFNs also enhance virus-induced apoptosis. Other IFN-α1 activities include enhancement of dendritic cell maturation and cytotoxic T cell activity. IFN-α1 binds to the IFN-αR1 and IFN-αR2 heterodimer.Intracellular signaling through the Jak/Stat pathway is best characterized. However, the PI3K, ERK, and p38 kinase pathways are also involved. The antiviral activities of the IFNs have led to their use in treating viral infections. Type I IFNs also appear to have an integral role in several autoimmune diseases.

序列:
氨基酸序列来源于:人/小鼠/大鼠源 TGF-β1(Ala279-Ser390)(P01137) 表达的蛋白片段。

标签:His-标签

活性:
Testing in progress.

蛋白长度:
The recombinant Human IFN-α1a Protein consists of 186 amino acids and predicts a molecular mass of 23 kDa.

分子:
IFN-α1a

检测指标:
IFN-α1a

产品形式:冻干粉,冻干缓冲液为无菌的20 mM PB,50 mM NaCl,pH 7.5。

重组人干扰素α1a(IFN-α1a)产品注意事项:
开盖使用前,请先离心。本产品为冻干粉,推荐用该产品配套的Reconstitution Buffer进行复溶,且浓度不低于100 μg/mL。客户可根据后续的实验需求,进行进一步的稀释。

警告:
本文列出的产品仅供研究使用,不适用于人类或临床诊断。我们产品所推荐应用,不是建议使用我们的产品去违反任何专利或许可证。对于使用本产品可能发生的专利侵权或其他违规行为,我们不承担任何责任。